pyrosequencing-based mgmtp methylation score (Pyrosequencing Inc)
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Pyrosequencing Based Mgmtp Methylation Score, supplied by Pyrosequencing Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pyrosequencing-based mgmtp methylation score/product/Pyrosequencing Inc
Average 90 stars, based on 1 article reviews
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1) Product Images from "Clinical value of the MGMT promoter methylation score in IDHmt low-grade glioma for predicting benefit from temozolomide treatment"
Article Title: Clinical value of the MGMT promoter methylation score in IDHmt low-grade glioma for predicting benefit from temozolomide treatment
Journal: Neuro-Oncology Advances
doi: 10.1093/noajnl/vdae224
Figure Legend Snippet: Association between progression-free survival (PFS) and the MGMTp methylation score. The association of the MGMTp methylation score, based on the MGMT-STP27 procedure, with progression-free survival (PFS; interval from diagnosis) was evaluated by the hazard ratio (confidence interval at 95%) from the cox regression model. The forest plots in A and B correspond to the PFS reported for patients treated in EORTC-22033 with temozolomide (TMZ) or radiotherapy (RT), respectively. , The MGMT-STP27 score was significant in the TMZ treated patients, but not in the patients with RT. The forest plots in C and D visualize the outcome of the Montpellier patients treated with TMZ, with time to progression defined by the next treatment-free survival (NxtTrtFS), and PFS defined by RANO, respectively. The MGMT-STP27 score was significant in the Montpellier cohort when using NxtTrtFS as outcome measure, a trend was observed when using RANO criteria for PFS. * P <.05; ** P <.01.
Techniques Used: Methylation, Biomarker Discovery